Pharma Supply & Access: Ghana’s heavy reliance on imported medicines (about 70%) is leaving its drug industry exposed to foreign shocks, with leaders calling for a push toward domestic manufacturing and jobs. Clinical Research in Animals: UC Davis is recruiting dogs for a glioma study (PRISM) to track tumor biology over time, with observational and radiation pathways. Cancer Care Updates: FDA granted accelerated approval to Bayer’s sevabertinib (Hyrnuo) for HER2-mutant NSCLC with activating TKD mutations, expanding beyond previously treated patients. Oncology Trial Signals: Tyra Biosciences reported early Phase 2 results for dabogratinib in FGFR3-altered low-grade NMIBC, with high response rates at 3 months. Cardiovascular Evidence: ACASA-TAVI trial results suggest anticoagulant monotherapy after TAVI may reduce leaflet thrombosis without worse bleeding or death versus aspirin. Obesity Treatment Research: The Endocrine Society urges obesity goals beyond weight loss and highlights major gaps in long-term safety and outcome measures. Health System Costs: A Georgetown report recommends caps on out-of-pocket costs and tighter deductible limits as insurers shift costs via prior authorization and higher deductibles. Digital Health & Security: Imprivata CEO warns AI agents need the same vetting and access controls as untrusted contract staff. Equity in Care: Australia’s “postcode penalty” shows regional cancer patients face major extra costs to access treatment.